Anyị maara na hyaluronic acid, dị ka ngwaahịa mara mma, nwere mmetụta na-ekpo ọkụ na nke na-eme ka ọ dị nro ma na-ejikarị ya na ngwaahịa nlekọta anụ ahụ dị iche iche dị ka ihe mkpuchi ihu, ude ihu na ihe ndị na-edozi ahụ. Site na mmepe nke sayensị na nkà na ụzụ na imeziwanye ụkpụrụ ndụ, nchụso ndị mmadụ na-achọ uwe abụghị naanị mara mma ma na-ekpo ọkụ, kamakwa ọ dị mma, enyi na gburugburu ebe obibi na ahụike. Dị ka akwa akwa na-arụ ọrụ nke nwere uru ọzọ, ọ na-ewu ewu karị. Mgbe hyaluronic acid na-ezute textiles, kedu ihe ọkụ ọkụ ọ ga-emepụta?
Kedu ihe bụ hyaluronic acid na gịnị bụ mmetụta ya?
Hyaluronic acid, nke a makwaara dị ka hyaluronic acid, bụ nnukwu polysaccharide nke mejupụtara nkeji disaccharide abụọ, D-glucuronic acid na N-acetylglucosamine. Hyaluronic acid bụ akụkụ dị mkpa nke njikọ anụ ahụ dị ka ihe intercellular mmadụ, ahụ vitreous, mmiri mmiri synovial nkwonkwo, ma na-arụ ọrụ dị mkpa nke anụ ahụ n'ịkwado mmiri, na-edobe oghere extracellular, na-achịkwa nrụgide osmotic, mmanụ mmanu, na ịkwalite nrụzi cell.
Kedu ihe bụ hyaluronic acid textiles? Olee uru ọ bara?
Akwa hyaluronic acid na-ezo aka na akwa nwere hyaluronic acid site na ijikọta mkpụrụ ndụ hyaluronic acid na eriri site na usoro mmecha. E jiri ya tụnyere ihe ịchọ mma, oge kọntaktị n'etiti textiles na ahụ mmadụ dị ogologo ma ebe kọntaktị dị ukwuu. Hyaluronic acid, ihe na-arụ ọrụ nke agbakwunyere na akwa ákwà, nwere ike nweta nlekọta ahụike anụ ahụ ruo n'ókè dị ukwuu. Ya mere, hyaluronic acid textiles na-ewu ewu na ndị na-azụ ahịa. Hyaluronic acid molecule nwere ọnụ ọgụgụ dị ukwuu nke hydroxyl dị iche iche na ndị ọzọ pola otu, nke nwere ike na-eme ka a na-aga n'ihu na-aga n'ihu na netwọkụ mmanụ aṅụ na-aga n'ihu na ntinye uche dị ala, na-eme ka hyaluronic acid, dị ka "ogbo molecular", nwere ike ịmịnye ma nọgide na-enwe 1000 ugboro nke ya. ịdị arọ nke mmiri, si otú ahụ na-eme ka ákwà ahụ dị nro ma dị mma, na-eme ka akpụkpọ ahụ dị nro ma ghara akọrọ. A na-amata hyaluronic acid n'ụwa niile dị ka onye na-ekpo ọkụ kachasị mma, nke nwere aha nsọpụrụ nke "ihe na-eme ka mmiri na-egbuke egbuke", na ọ bụkwa glycosaminoglycan, nke na-enweghị ụdị ụdị, ndakọrịta dị mma, na ọ gaghị akpata mmeghachi ahụ nfụkasị na nsogbu nchekwa.
Kedu ka esi emepụta ma hazie akwa hyaluronic acid?
Ka ọ dị ugbu a, e nwere ụzọ anọ bụ isi nkwadebe nke akwa nwere hyaluronic acid: usoro ntinye mpịakọta, usoro microcapsule, usoro mkpuchi na usoro eriri. Usoro ntinye bụ ụdị usoro nhazi nke na-eji onye na-emecha ihe nwere hyaluronic acid na-emeso ákwà ahụ site na ntinye usoro. Usoro a dị mfe, dị mfe ma dị irè, a na-ejikarị ya eme ihe ugbu a. Usoro Microcapsule bụ usoro nke na-eji ihe na-emepụta ihe nkiri na-ekechi hyaluronic acid na microcapsules, wee dozie microcapsules na eriri ákwà. Usoro a nwere ike nweta akwa akwa nwere mmiri na-adịgide adịgide. Usoro mkpuchi na-etinyekarị hyaluronic acid n'elu eriri eriri site na nkà na ụzụ nke onwe nke electrostatic, nke dị mgbagwoju anya na nke na-adịghị etinye ya. Usoro eriri bụ usoro ịgbakwụnye hyaluronic acid n'ime ngwọta ngwaahịa na-agbagharị wee tụgharịa. Usoro a nwere ike nweta akwa akwa hyaluronic acid nwere ogologo ogologo oge, ma bụrụkwa ntụzịaka nke nhazi nnukwu akwa hyaluronic acid n'ọdịnihu.
Kedu ka esi amata ma enwere hyaluronic acid na textiles?
N'ozuzu, textiles nwere hyaluronic acid enweghị ike ịmata ọdịiche dị na nlele anya, yana ọ na-esikwa ike ịmata ọdịiche dị n'ụdị mmetụta aka. Ya mere, ọ dị mkpa iji nyochaa ma textiles nwere ihe hyaluronic acid na-eme ka ahụ dị nro site n'enyemaka nke ngwa ngwa. Ka ọ dị ugbu a, e nwere ụzọ atọ isi chọpụta ọdịnaya nke hyaluronic acid: colorimetry, mwepu olu dị elu nke chromatography mmiri mmiri na chromatography mmiri mmiri dị elu. Usoro colorimetric nwere nkọwa na-adịghị mma ma dị mfe ịmegharị ya, nke nwere ike ibute nsonaazụ ule na-ezighi ezi na nsonaazụ ụgha. Mwepu nke olu chromatography mmiri mmiri na-arụ ọrụ dị elu na-enwekarị oke nchọpụta dị elu, nke ọdabara maka ịchọ mma nwere nnukwu ọdịnaya nke hyaluronic acid, mana ọ bụghị maka akwa nwere obere ọdịnaya. A na-ekewa chromatography mmiri mmiri dị elu ugbu a na acidolysis - precolumn derivatization - chromatography mmiri na-arụ ọrụ dị elu na enzymolysis - chromatography mmiri mmiri dị elu. N'ime ha, acidolysis - precolumn derivatization-ule ọrụ nzọụkwụ na-akpa ike, na reproducibility nke ule pụta kwesịrị ka mma, otú a na-erughị etinyere usoro; N'ihi nkọwa dị mma nke enzyme na otu ngwaahịa enzymolysis, enzymolysis nwere nkọwa siri ike na nke ziri ezi dị elu, ma jiri nwayọọ nwayọọ tinye ya na nyocha nke ọdịnaya hyaluronic acid n'ụdị mgbagwoju anya.
Oge nzipu: Mar-17-2023